The Best Spray Hand Sanitizer for 2022 (Which is Better)

Let’s face at this moment worldwide is COVID-19. The Best Spray hand sanitizer you’ve been hearing since childhood, but we’ll say it again for the people in the back: Keeping your hands clean is the easiest way to prevent sickness and stop the spread of germs.

It’s not just a statement beloved by moms and kindergarten teachers, but a fact shared by the Centers for Disease Control and Prevention (CDC).

Best Spray Hand Sanitizer

While a thorough scrub-down with soap and water is the most effective way to clean your hands—it’s the best cleaning method for removing germs like norovirus, Cryptosporidium, and Clostridium, according to the CDC you won’t always have access to a sink.

And even if a sink is nearby, washing your hands after every single exposure to a dirty surface (so, basically every second) can start to feel like an obsessive, time-sucking venture. Instead, it’s worth trying an alcohol-based hand sanitizer.

To help you discover the simplest sanitizers that meet CDC requirements, we collected the highest picks available to buy online immediately. Unfortunately, traditional options like GermX and Purell are limited due to the ongoing novel coronavirus (COVID-19) outbreak.

But the good news is that there is still plenty of top-rated hand sanitizing products available to stock up on now so you can stay as healthy as possible. Here are the best spray hand sanitizers:

The 30 Best Spray Hand Sanitizer Reviews 2022

1. Best Scent: Megababe Squeaky Clean Spray Hand Sanitizer

Unlike many other hand sanitizers on the market, Megababe’s plant-based option smells like calming bergamot and citrus peel instead of alcohol.

Every spritz delivers a 60% alcohol concentration to kill fungus, germs, and microbes without leaving your skin with a sticky residue.

Megababe Squeaky Clean Spray Hand Sanitizer

You’ll also love that the vegan formula doesn’t dry out the skin and boasts nourishing ingredients like marula oil, almond oil, and burn plant. It’s available in both a small 2-ounce container or a 16-ounce pump container.

2. Babyganics Alcohol-Free Foaming Spray Hand Sanitizer

“While not as effective, alcohol-free hand sanitizers are often utilized in a pinch if you’ve got sensitive skin,” says Zeichner.

This version from Babyganics is available in fragrance-free or mandarin orange. (Keep in mind that alcohol-free sanitizers aren’t a substitute for soap and water.)

Babyganics Alcohol-Free Foaming Spray Hand Sanitizer

3. Best Sustainable: by Humankind Spray Hand Sanitizer

Wellness brand by Humankind is all about promoting a more sustainable lifestyle, and its latest launch is no exception.

Its ethically-made hand sanitizer available in grapefruit or unscented formulas boasts a 65% alcohol concentration and hyaluronic acid, an anti-aging ingredient that helps skin hold water.

by Humankind Spray Hand Sanitizer

In an attempt to scale back waste, the brand’s 8-ounce bottle is formed from aluminum and holds enough product to refill a pocket-sized bottle 4 times. Plus, $1 from every hand sanitizer sold is donated to The Robin Hood Relief fund in NY City.

4. Purell Advanced Spray Hand Sanitizer Refreshing Gel

Zeichner uses Purell before and after seeing each patient which suggests sanitizing about 80 times per day. “It contains 70 percent alcohol, effectively disinfects the skin, and doesn’t dry out my hands,” he says.

Purell Advanced Spray Hand Sanitizer Refreshing Gel

5. Best Scent: Vegamour Hand Sanitizer Spray

Vegamour’s plant-based option smells like calming lavender and citrus peel, and it delivers a 75% alcohol concentration in every spray.

The vegan ingredients won’t dry out hands because of skin-friendly agents like marula oil and burn plants.

Vegamour Hand Sanitizer Spray

6. Primally Pure Spray Hand Sanitizer

Primally Pure’s Hand Sanitizer gives your hands consciously formulated protection against all kinds of germs. It contains 63 percent grape seed oil alcohol to kill viruses and other harmful bacteria.

It’s also made with organic essential oils like lavender and tea tree to soothe irritation.

Primally Pure Spray Hand Sanitizer

7. Best Hydrating: Pipette Hand Sanitizer

Baby brand Pipette created this fragrance-free gel to offer small hands a secure sanitizer. You’ll still find the CDC-recommended alcohol level, 65%, within the formula.

But it also includes a dose of hydrating squalane oil and glycerin. That means you’ll calculate hands that are sanitized and soft—no cream necessary.

Pipette Hand Sanitizer

8. Eir NYC Pure Eir Sanitizing Spray

Eir NYC’s Pure Eir hand sanitizer mixes a 65.7 percent alcohol formula with calendula and vegetable oil to hydrate skin and witch hazel to assist kill germs. It also features a lovely citrus scent, so there is no medicinal smell.

Eir NYC Pure Eir Sanitizing Spray

9. Best Bulk: NXN Beauty Advanced Hand Sanitizer

Reduce waste by opting for a bulk container of hand sanitizer like this almost-34-ounce pick. Its pump dispenser makes applying the fast-drying gel a breeze—and you’ll love that it has a 70% ethyl alcohol concentration, but still smells like lavender. Plus, it arrives at most addresses in under a week.

NXN Beauty Advanced Hand Sanitizer

10. CHI Organic Gardens Moisturizing Hand Sanitizer

CHI’s hand sanitizer comes in four sizes and houses an organically grown burn plant, essential nutrients, and glycerin to lock in moisture long after it’s applied.

And it’s 77 percent ethyl alcohol, which is well above the CDC’s recommended 60 percent.

CHI Organic Gardens Moisturizing Hand Sanitizer

11. Most Potent: Peter Thomas Roth Hand Sanitizer

Celebrity-adored skincare brand Peter Thomas Roth launched its first-ever hand sanitizer in April, and it doesn’t disappoint. The 2-ounce bottle contains the highest alcohol concentration on this list, 80%, along with a hydrating boost of glycerin.

Peter Thomas Roth Hand Sanitizer

Plus, your purchase supports the beauty brand’s initiative to give up to 5,000 bottles of the sanitizer to New York’s largest healthcare provider, Northwell Health Hospitals.

12. Bare Republic Bare Hands Sanitizer Spray

Bear Republic’s plant-based Bare Hands Sanitizer Spray keeps hands bacteria-free with a 60+ percent alcohol formula with aloe, glycerin, and calendula, and chamomile extracts for an additional refreshing element.

Bare Republic Bare Hands Sanitizer Spray

13. Best Vegan: Previse Hand Sanitizer

Previse pivoted production handy sanitizer overnight after coronavirus caused a spike in demand. The indie brand kept skincare in mind when developing the sanitizer.

Combining necessary ingredients like 75% alcohol and peroxide with a hydrating boost of glycerin to stop the skin from drying out post-application. And yes, it’s still vegan.

Previse Hand Sanitizer

14. Public Goods Hand Sanitizer

Public Goods’ pocket-size hand sanitizer is important and easy because it should be. This lightly fragranced version contains ethyl alcohol and glycerin to kill 99.9 percent of germs, while burn plant gel keeps your hands as soft as possible.

Public Goods Hand Sanitizer

15. Best Ingredients: Lather Hand Sanitizer with Moisturizing Aloe

The rush to produce hand sanitizer led many brands to streamline their ingredients—but not Lather.

The beauty and wellness brand developed a potent moisturizing formula by infusing its 65% alcohol concentration with skincare powerhouses like aloe vera, green tea extract, glycerin, witch hazel, and yucca. It’s available in a 3-pack or a 6-pack.

Lather Hand Sanitizer with Moisturizing Aloe

16. Honest Hand Sanitizer Spray

“This is a plant-based sanitizer that effectively kills 99.9 percent of germs and bacteria,” says Frieling. It’s formulated with naturally derived glycerin and aloe, which help combat the drying effect of some sanitizers, leaving hands moisturized.

Honest Hand Sanitizer Spray

17. Best Fragrance-Free: Eczema Honey Hand Sanitizer Gel

If you’re sensitive to fragrance, this unscented option should be your go-to. It only has 4 ingredients—including 70% ethyl alcohol—and skips out on potential irritants.

Plus, the 8-ounce size will keep you well-stocked whether it becomes a new office staple as lockdown restrictions lift or find a permanent spot in your home entryway.

Eczema Honey Hand Sanitizer Gel

18. By Humankind Hand Sanitizer Refills

By Humankind bulk bottles are made of recyclable aluminum and designed to refill the plastic, single-use sanitizer bottles (of every size) you already have.

The sanitizer contains 65 percent alcohol, plus mucopolysaccharide for extra moisturizing benefits, and comes in two varieties:

By Humankind Hand Sanitizer Refills

Unscented and Grapefruit. $1 of every hand sanitizer sold goes to The Robin Hood Relief Fund.

19. Best Pre-Order: Skylar Hand Sanitizer Gel

Start stocking up for summer by placing a pre-order for Skylar’s sanitizing gel now. The skincare brand’s latest launch boasts 62% alcohol with naturally soothing additions like witch hazel.

You’ll love that it smells like Skylar’s signature scent—jasmine tea and lemon leaves—and comes in an 8-ounce pump bottle.

Skylar Hand Sanitizer Gel

Better yet, the brand is donating part of the profits from its first production to UCLA Medical Center in Los Angeles and Mount Sinai Hospitals in New York City.

20. Clark’s Botanicals Hand Sanitizer

Clark’s Botanicals Hand Sanitizer contains a considerable 71 percent ethyl alcohol to offer you a touch of peace of mind once you do not have access to a sink and good’ soap and water.

Clark's Botanicals Hand Sanitizer

The brand has redirected one hundred pc of its production handy sanitizers, is making a gift of bottles with a sale of any full-size product and is donating bottles to New York-based Northwell Health and Montefiore hospitals.

21. 100% Pure Hand Sanitizer Spray

The 100% Pure Sanitizer Spray is 62 percent alcohol, but it also contains tea tree oil, which has antibacterial properties, also as burn plant and glycerin to appease irritation and keep your hands from drying out.

100% Pure Hand Sanitizer Spray

As an added bonus, the brand will donate sanitizers to HealthRIGHT 360, a San Francisco-based nonprofit that provides healthcare services to the homeless and low-income residents statewide to help in the effort against COVID-19.

100% Pure also launched a multipurpose Hand & Surface Cleansing Spray that’s formulated with skin-softening burn plant and vegetable glycerin.

Also as 70 percent ethyl alcohol and antibacterial lemon essential oil so you can keep your hands and non-porous surfaces, such as grocery carts or door handles, clean at the same time.

22. Pipette Spray Hand Sanitizer

Pipette’s fragrance-free offering eliminates 99.99 percent of bacteria, because of 65 percent ethyl alcohol and its hero ingredient, sugarcane-derived squalane, so your hands stay super soft.

It first launched in an eight-ounce bottle but Pipette now also sells a two-ounce bottle, and jumbo 32-ounce bottles are available for preorder.

Pipette Spray

23. Peter Thomas Roth Hand Sanitizer Alcohol Antiseptic 80% Topical Solution

You can count the ingredients in Peter Thomas Roth’s Hand Sanitizer Alcohol Antiseptic 80% Topical Solution on one hand: 80 percent alcohol, glycerin, hydrogen peroxide, and purified water USP.

Peter Thomas Roth

It’s effective, no-frills, and comes in a six oz. bottle, which means you won’t run out of sanitizer as quickly.

24. Pacifica Aloe BFF Hand Antiseptic

Over the past few months, we think it’s safe to say that hand sanitizer has become one of your best friends. Yes? Well, Pacifica’s Aloe BFF Hand Antiseptic shouts out that relationship both in its name and content.

Which incorporates 62 percent alcohol, also as aloe, chamomile, and calendula to moisture and calm skin. Its container is also made out of 100 percent post-consumer recycled (PCR) plastic.

Pacifica Aloe BFF

25. Neo-Medical 62% Alcohol Hand Clean Sanitizing Gel

Neo-Medical 62% Alcohol Hand Clean Sanitizing Gel seamlessly joins effective and calming properties together. The key ingredients are 62 percent ethanol alcohol, green tea.

Aloe vera to soothe dry, inflamed skin, and sodium hyaluronate to draw in moisture to the skin and keep dryness and flakiness at bay.

Neo-Medical 62% Alcohol

Since it comes during a whopping 16.9 oz bottle, it’s perfect to stay around the house for cleaning hands and surfaces.

26. The Crème Shop Moisturizing Sanitizer

The Crème Shop’s Moisturizing Hand Sanitizer delivers 70 percent ethanol in an easy-to-pack pouch. The Green Tea version is pictured but it’s also available in Mixed Berries, in case you want to switch up your scents. Both are available in a slightly larger 2 oz size as well.

The Crème Shop Moisturizing

27. Milani Rose Sanitizer

Armed with 68 percent ethanol alcohol and glycerin, Milani’s Rose Hand Sanitizer comes in a handy spray format that keeps hands clean and moisturized.

And best yet, with each purchase, made on, the brand also will donate one unit to The Downtown Women’s Center.

Milani Rose

28. Tonymoly 61.5% Alcohol Derma Masterlab Spray

If you prefer a spray version, there’s the Tonymoly 61.5% Alcohol Derma MasterLab Hand Spray to keep things light. True to its name, it has 61.5 percent alcohol, as well as Centella Asiatica to soothe skin.

29. Physicians Formula Rosé Take the Germs Away Sanitizer

Physicians Formula’s Rosé Take the Germs Away Hand Sanitizer is loaded up with 80 percent ethyl alcohol to kill bacteria, additionally to tea tree oil and aloe for conditioning and softening hands. As the name suggests, it smells like a lovely rose garden.

30. Nudestix Antibacterial Hand Gel

As you can see, Nudestix’s Antibacterial Hand Gel comes in three sizes for your varying needs: 3.3- and 16.9-ounce bottles, and 1-ounce pouches (sold in packs of five) that you can clip onto your key rings for easy access.

While sold at Sephora, for each purchase specifically made on, the brand is donating a hand sanitizer pouch to the foremost at-risk communities.

Nudestix has also committed to donating over 20,000 sanitizers to frontline workers and wonders retail workers.

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